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Our first parents, by this sin, fell from their original righteousness and communion with God, and we in them whereby death came upon all:3 all becoming dead in sin,4 and wholly defiled in all the faculties and parts of soul and body.5

 
3 Rom. 3:23
4 Rom 5:12, etc.
5 Titus 1:15; Gen. 6:5; Jer. 17:9; Rom. 3:10–19

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They being the root, and by God's appointment, standing in the room and stead of all mankind, the guilt of the sin was imputed, and corrupted nature conveyed, to all their posterity descending from them by ordinary generation,6 being now conceived in sin,7 and by nature children of wrath,8 the servants of sin, the subjects of death,9 and all other miseries, spiritual, temporal, and eternal, unless the Lord Jesus set them free.10

 
6 Rom. 5:12–19; 1 Cor. 15:21–22,45,49
7 Ps. 51:5; Job 14:4
8 Eph. 2:3
9 Rom. 6:20, 5:12
10 Heb. 2:14–15; 1 Thess. 1:10